Medical Questions and Answers

It’s true that after a kidney transplant, there is always a possibility of developing anti-GBM antibodies, especially in patients with Alport syndrome. However, if you are under a strict immunosuppressive regimen, the chances of recurrence of these antibodies

You're absolutely correct that graft failure can be more common among kidney transplant recipients with Alport syndrome, especially due to the presence of anti-GBM disease. This is because Alport syndrome can cause an abnormal immune response, increasing the

The HLA haplotype most strongly associated with anti-GBM antibody disease, particularly in cases of Goodpasture syndrome, is the HLADRB1*1501 allele. Studies have shown that individuals with this specific allele, along with the DRB1*1401 and DRB1*1101 alleles,

Concerning your elevated uric acid levels, this suggests a need to adjust your diet. I recommend reducing your intake of animal products, particularly red meat, organ meats, and seafood, as these are rich in purines, which can contribute to high uric acid

One potential rare consequence of shock wave lithotripsy in susceptible individuals is the development of lower ureteral stenosis. This can occur when there is scarring or narrowing in the ureter as a result of the shock waves. In such cases, it's important

Yes, certainly. The symptoms you're describing—fatigue, swelling, changes in urination, and difficulty concentrating—can be indicative of uraemic syndrome, which occurs when the kidneys are not effectively filtering waste products from the blood. This can lead

Changes in diet and lifestyle can have a significant impact on kidney disease management. For example, controlling your salt intake can help regulate blood pressure, which is crucial for kidney health. Additionally, adjustments to your diet can improve your

Swelling in the legs, ankles, and face could be a sign of a condition called nephrotic syndrome, which involves the kidneys not functioning properly. This condition often leads to fluid retention and can cause swelling, also known as edema. To evaluate your

Nephrotic syndrome is a kidney disorder that causes your body to excrete too much protein in the urine, leading to fluid retention and swelling. In some cases, fluid can accumulate in the pleural space around the lungs, leading to pleural effusion, which is

These symptoms, such as throat infections, skin rashes, or gastrointestinal issues like diarrhea or nausea, could potentially provoke or indicate an underlying condition like intrinsic kidney disease. It’s important to carefully monitor any such symptoms as