Is Graft Failure a Concern After Your Kidney Transplant? Get Guidance!

Published on, 30 May, 2025. Answered by Dr. Claudine Christiaens and Verified by Dr.Galen Team
Patient Question

Hello Doctor,

 

I have been diagnosed with Alport syndrome, and I’ve heard that graft failure can happen more often in kidney transplant patients with this condition, especially due to anti-GBM disease. Could you please explain why this happens and what risks I should be aware of after my transplant? 

 

Hello

Thank you for reaching out to Dr. Galen. Please find the below response to your query.

 

You're absolutely correct that graft failure can be more common among kidney transplant recipients with Alport syndrome, especially due to the presence of anti-GBM disease. This is because Alport syndrome can cause an abnormal immune response, increasing the risk of rejection or damage to the transplanted kidney.

 

To reduce the risk of graft failure, a very strict immunosuppressive treatment regimen is required. These medications help prevent your body from attacking the new kidney, ensuring that the transplant is accepted and functions properly. It's important to follow your doctor’s instructions closely when it comes to taking these medications, as well as attending regular follow-up appointments to monitor for any signs of rejection or complications.

 

By maintaining a strict immunosuppressive plan and working closely with your healthcare team, you can significantly improve the chances of long-term success with your kidney transplant.

 

Thanks

 


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