Hello Doctor,
I recently received a kidney transplant from a healthy donor, and I have Alport syndrome. I’m concerned about the possibility of developing anti-GBM antibodies post-transplant. Can you tell me what percentage of kidney recipients with Alport syndrome develop these antibodies, and if so, how can it affect my health or transplant success?
Hello
Thank you for reaching out to Dr. Galen. Please find the below response to your query.
It’s true that after a kidney transplant, there is always a possibility of developing anti-GBM antibodies, especially in patients with Alport syndrome. However, if you are under a strict immunosuppressive regimen, the chances of recurrence of these antibodies are significantly reduced.
The immunosuppressive medications you are taking are designed to prevent your body from rejecting the new kidney and also help in minimizing any autoimmune reactions, including the development of anti-GBM antibodies. It’s essential to follow your prescribed treatment plan carefully and attend regular follow-up appointments with your transplant team to monitor your kidney function and antibody levels.
While the risk is low with proper management, it’s important to stay vigilant and report any unusual symptoms to your healthcare provider as soon as possible.
Thanks
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