Can You Take Hydroxyzine with Prednisone?

Published on, 20 April, 2025. Answered by Dr. Hans Unim and Verified by Dr.Galen Team
Patient Question

Hello Doctor,

 

Is it safe to take hydroxyzine and prednisone together? I was prescribed both for my allergies and inflammation, but I’m worried about any potential interactions or side effects. Should I be concerned about drowsiness or other issues?

 

Answered by Dr. Hans Unim

Hello,

Thank you for reaching out to Dr. Galen. Please find the below response to your query.

 

You haven't specified your clinical symptoms in the question. However, in general, hydroxyzine, a potent antihistamine, can be taken with prednisone if your allergic reaction involves significant inflammation. While there are no major contraindications, combining these medications may increase drowsiness or other side effects in some individuals. For a more accurate assessment and to ensure the safest treatment for your specific condition, I advise consulting a doctor.

 

Thanks

 


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About Dr. Hans Unim

Dr. Hans Unim

Family Practice / General Practice

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