Things to note:- The most important aspect of management is the discontinuation of antibiotics.
- Rehydration may be required. This should be done with the Oral Rehydration Solution (ORS) unless the patient is vomiting or dehydrated.
Surgery for bowel perforation.
Medical Treatment:- Loperamide is contraindicated as it may result in toxic megacolon.
If diarrhoea does not settle on antibiotic withdrawal or if pseudomembranous colitis is present:
- Vancomycin, oral, 125 mg 6 hourly.
OR
- Metronidazole, oral, 800 mg 8 hourly for 10 days.