How to Treat Antibiotic Induced Diarrhoea?

Things to note:

• The most important aspect of management is the discontinuation of antibiotics.
• Rehydration may be required. This should be done with the Oral Rehydration Solution (ORS) unless the patient is vomiting or dehydrated.
  Surgery for bowel perforation.

Medical Treatment:

• Loperamide is contraindicated as it may result in toxic megacolon.

If diarrhoea does not settle on antibiotic withdrawal or if pseudomembranous colitis is present:

• Vancomycin, oral, 125 mg 6 hourly.

OR

• Metronidazole, oral, 800 mg 8 hourly for 10 days.