Your Guide to Typhoid Vaccines and Expert Consultations

Hello,

Thank you for reaching out to Dr. Galen. Please find the below response to your query.

There are two types of vaccines available to prevent typhoid fever: an inactivated (killed) vaccine and a live, attenuated (weakened) vaccine. Your healthcare provider can help determine which type of typhoid vaccine is most suitable for you.

The inactivated typhoid vaccine is given as an injection and is approved for individuals aged 2 years and older. It is recommended to receive one dose at least two weeks prior to travel, with booster doses every two years for those who remain at risk.

The live typhoid vaccine is administered orally and is suitable for individuals aged 6 years and older. This vaccine consists of four capsules, taken every other day, with the final dose taken at least one week before travel. Each capsule should be swallowed whole (not chewed) about an hour before meals, using cold or lukewarm water. A booster is recommended every five years for those at continued risk.

It's important to note that live typhoid vaccine capsules must be refrigerated and should not be frozen. While routine typhoid vaccination is not generally recommended in the United States, the vaccine is advised for:

• Travelers to regions where typhoid fever is common (Note: the vaccine is not 100% effective and should not replace caution regarding food and drink consumption).
• Individuals who have close contact with a typhoid carrier.
• Laboratory personnel working with Salmonella typhi bacteria.

Typhoid vaccine can be administered simultaneously with other vaccines.

Thanks