How to Treat Neuroblastoma?

What is Neuroblastoma?

Neuroblastoma, an uncommon and aggressive type of cancer predominantly affecting young children, arises from immature nerve cells referred to as neuroblasts. These cells are commonly found in the adrenal glands positioned on top of the kidneys. Nevertheless, neuroblastoma can also manifest in various regions such as the abdomen, chest, neck, and near the spine. It stands as the most prevalent extracranial solid tumor in childhood, frequently appearing in children under the age of five.

This pediatric cancer emerges within the nervous system of infants and young children, originating from neuroblasts found in the adrenal glands, crucial organs regulating automatic bodily functions. While its primary development occurs in the adrenal glands, neuroblastoma can extend to nerve tissue in the spinal cord, abdomen, chest, or neck, posing the risk of metastasis to other areas of the body.

Why is Neuroblastoma Challenging to Treat?

Neuroblastoma poses significant challenges in terms of treatment due to its varied presentation and the fact that it often advances to a high-risk stage before detection. Additionally, the disease may spontaneously regress in some cases, making it difficult to predict its course accurately. The heterogeneity of neuroblastoma and its potential to metastasize to distant organs further complicate treatment strategies.