How to Treat Pagets Disease Of The Nipple?

  • November 10, 2023
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How to Treat Pagets Disease Of The Nipple?

What is Paget's Disease of the Nipple?

Paget's Disease of the Nipple, or Paget's disease of the breast, is a rare form of breast cancer that primarily affects the nipple and surrounding areola. Named after Sir James Paget, it involves changes in the nipple's skin, appearing red, scaly, and inflamed. Despite being localized, the disease often extends to the ducts beneath the skin, making diagnosis and treatment more complex than other breast cancers.

This rare breast cancer, also known as mammary Paget's disease, presents as stage 0 breast cancer confined to the nipple or coexists with invasive breast cancer in the milk ducts. It resembles eczema on the nipple, initially mistaken for a common rash, with symptoms such as itching, scaling, red plaques, and nipple discharge. While not everyone with these symptoms has Paget's disease, for those who do, they may signal an underlying breast cancer.

Why Does Paget's Disease Occur?

The exact cause of Paget's Disease of the Nipple remains unclear. However, it is widely believed to be associated with underlying breast cancer, particularly ductal carcinoma in situ (DCIS). DCIS is a non-invasive form of breast cancer that starts in the milk ducts and may progress to invasive cancer if left untreated. Paget's Disease is thought to occur when cancer cells from DCIS migrate to the surface of the nipple, causing the characteristic skin changes.