How to Treat Glomerular Disease And Nephritic Syndrome?

What is Glomerular Disease and Nephritic Syndrome?

Glomerular disease and nephritic syndrome pertain to kidney conditions, particularly affecting the glomeruli, tiny blood vessels responsible for filtering waste and excess fluids to form urine. Glomerulonephritis, a type of kidney disease, involves damage to these glomeruli, causing difficulties in waste and fluid removal. While milder cases often resolve with treatment, severe conditions can lead to kidney failure. Therefore, understanding these conditions is crucial for early identification and effective management.

Why Do Glomerular Disease and Nephritic Syndrome Occur?

1. Infections: Infections, particularly those affecting the respiratory or urinary tracts, can trigger an immune response that may lead to inflammation in the glomeruli. Streptococcal infections, for example, are associated with the development of post-streptococcal glomerulonephritis.
2. Autoimmune Disorders: Disorders such as lupus and vasculitis involve the immune system mistakenly attacking the body's own tissues, including the glomeruli. This autoimmune response can result in ongoing inflammation and kidney damage.
3. Diabetes: Individuals with diabetes, especially uncontrolled diabetes, are at an increased risk of developing diabetic nephropathy. Persistent high blood sugar levels can damage the blood vessels in the kidneys, leading to glomerular dysfunction.
4. Medications: Certain medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and some antibiotics, can cause kidney damage and contribute to glomerular disease. It is essential to be aware of potential side effects and consult a healthcare professional if concerns arise.

How to Identify Glomerular Disease and Nephritic Syndrome?

Prompt recognition of signs and symptoms is vital for early diagnosis and effective management. Individuals should be vigilant for the following indicators

1. Hematuria (Blood in the Urine): The presence of blood in the urine may be a sign of glomerular disease. Urine that appears pink, red, or brown should be investigated promptly.
2. Edema (Swelling): Swelling, particularly in the legs, ankles, or face, may occur due to fluid retention resulting from impaired kidney function. 
3. High Blood Pressure: Elevated blood pressure can be both a cause and a consequence of glomerular disease. Regular blood pressure monitoring is essential for early detection. 
4. Decreased Urine Output: Changes in urine output, including decreased volume or frequency, may indicate kidney dysfunction and should be evaluated by a healthcare professional.