How to Treat Anticoagulant Poisoning?
- July 26, 2023
- No Comments
Things to note:
- Reanimation,
- Stop warfarin in therapy patients.
For patients on warfarin therapy
- 10 mg of vitamin K1, IV / IM.
- Depending on INR response, may be repeated.
- Note the effective delay.
- Patients who bleed need additional fresh frozen plasma and the first dose of vitamin K intravenous. Follow- up doses may be required for any route if INR continues to increase, as vitamin K has a shorter half- life than warfarin.
- The administration of vitamin K1 may induce warfarin resistance. Patients receiving chronic warfarin therapy and who are at high risk for thrombo- embolic complications but do not actively bleed with INR between 5 and 9:
- Admit hospital patients and monitor. Give fresh frozen plasma( FFP) if bleeding occurs.
- Vitamin K1, IV, 0.5-1 mg low dose if FFP is not available.
- K1, IV vitamin, 2.5 mg
Oral, vitamin K1, 5 mg.
- Parenteral formulation may be used for oral administration of low doses.
Super warfarins
- Vitamin K1 treatment must be prolonged for several months, as these substances are very long- acting. Clinical response to INR monitor.
Comments (0)
No comments yet