How to Treat Thrombotic Thrombocytopenic Purpura Haemolytic Uraemic Syndrome?

Medical Treatment:
In HIV-associated thrombotic thrombocytopenia, start combination antiretroviral therapy urgently.
  • Fresh frozen plasma, IV infusion, 30 mL/kg in 3-4 divided doses.
It is necessary to discuss the use of platelet transfusions with a specialist.

When to refer:
  • All patients - Discuss with a haematologist.