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How to Treat Hyperemesis Gravidarum?

Things to note:
  • Counselling.
  • Frequent small, dry meals.
  • Avoid fatty and spicy foods.
  • Restrict oral intake for 24-48 hours, but ensure adequate intravenous hydration.

Medical Treatment:
Correct electrolyte imbalance with IV fluids.
  • Pyridoxine, oral, 25 mg 8 hourly.
  • Metoclopramide, oral/IV, 10-20 mg 6 hourly as needed.
  • Vitamin B complex, IV, 10 mL.
In refractory cases:
Administer daily until hyperemesis is controlled:
  • Dexamethasone, IM/IV, 4-8 mg daily.
  • Ondansetron, IV, 4-8 mg over 5 minutes, daily.